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Rosharon TX Communities Near Highway 288 in Brazoria County Rosharon TX is located along the Highway 288 corridor south of Houston and spans parts of Brazoria County and nearby Fort Bend County. The area includes newer master planned communities such as Meridiana, Sierra Vista, and Sterling Lakes along with some acreage properties. Highway 288 and the toll lanes provide access toward the Texas Medical Center, downtown Houston, Pearland, and Manvel. Neighborhoods are served by Alvin ISD or Fort Bend ISD depending on location.