12460 S Us Highway 181 is listed for sale at $ 315,000. The Single-Family property has 5 bedrooms, 2 Full Bathrooms, 1404 square feet and was built in 1979. The lot size is 0 Square feet. BRLocated at 12460 S US Highway 181 in San Antonio, Texas, this versatile commercial property offers an excellent opportunity along one of the area’s primary corridors connecting San Antonio to Floresville and the surrounding communities. Situated on a 0.32+/- acre lot with convenient access to Loop 1604, the property benefits from strong visibility and easy accessibility in a rapidly growing area. The 1,895+/- square foot building features a functional layout that includes a full kitchen, two full bathrooms, and five additional rooms, making it well suited for a variety of office, medical, professional, or service-based uses. With direct frontage on US Highway 181 and ample potential for owner-users or investors alike, this property offers flexibility in a highly accessible San Antonio location.